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It is important to note that, in the other large type 2 diabetes cardiovascular outcome trials, there were no statistically significant associations with the use of GLP-1/GIP agonists and negative eye outcomes
Thus, integration of both hormones into a single molecule may not only maximize the metabolic efficacy of the individual signals, but allow also specific delivery of estrogen into GLP1 receptor-expressing cells, avoiding potential undesired effects of estrogen on reproductive tissues, as shown also in our studies
By regularly tracking these metrics, you and your healthcare provider can determine how effective the therapy is and tweak your plan if needed
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