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When symptoms are attributed to high B12 intake, they typically include: Skin reactions : Acne-like eruptions or rosacea-type rashes, particularly with hydroxocobalamin injections (listed as rare adverse effects in the product information) Gastrointestinal disturbances : Mild nausea, diarrhoea, or abdominal discomfort Headaches : Occasional reports of headache following B12 injections Anxiety or restlessness : Anecdotal reports, though causation remains unestablished It is crucial to distinguish between symptoms caused by elevated B12 levels and those arising from the underlying conditions that elevate B12
P., Samper, E., Lansdorp, P
Contemp Issues Edu Res (CIER)
Although analgesics such as NSAIDs are widely used for pain control, they cause some adverse reactions such as upper gastrointestinal bleeding [1, 2, 3]
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