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Description

18 Mycotoxins break down the blood-brain barrier and damage cells that produce myelin (oligodendrocytes)

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10.1172/JCI38940 15 ChangC.WorleyB

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Physicochemical Profile Appearance: Bluetinted lyophilized powder (due to Cu coordination) Solubility: Soluble in aqueous buffers (mild acidic to neutral pH) Stability: Stable under dry, refrigerated conditions

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Therefore, TRIP12-mediated K29-ubiquitylation is required to counteract OTUD5 DUB activity, similar to the OTUD5 degradation mechanism

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