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Une supplmentation, sur prescription mdicale , est galement ncessaire : En cas de dficit hrditaire (trs rare) ou conscutif une maladie du foie (altrant sa production) ou des reins (augmentant les pertes, notamment en cas dhmodialyse)

Betz R, Petukhova L, Ripke S, Huang H, Menelaou A, Redler S, Becker T, Heilmann S, Yamany T, Duvic M, Hordinsky M, Norris D, Price V, Mackay-Wiggan J, de Jong A, DeStefano G, Moebus S, Bhm M, Blume-Peytavi U, Wolff H, Lutz G, Kruse R, Bian L, Amos C, Lee A, Gregersen P, Blaumeiser B, Altshuler D, Clynes R, de Bakker P, Nthen M, Daly M, Christiano A (2015) Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci

In RA pathogenesis, activated RA fibroblast-like synoviocytes (RA-FLSs) exhibit proliferative features similar to tumor cells and subsequently cause cartilage erosion, which will eventually lead to joint destruction ( It has been hypothesized that iron is excessively accumulated in the synovium of RA patients to perpetuate inflammation ( 2 Overview of ferroptosis Cell death is a fundamental physiological process in all aspects of life

doi:10.1167/iovs.15-18637 30