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Turbulent flow promotes NF-B and AP-1 activity that upregulate pro-inflammatory and pro-atherogenic genes such as ICAM-1, E-selectin, platelet-derived growth factor (PDGF)-BB, IL-1a, bone morphogenic protein-4 (BMP-4), monocyte chemotactic protein-1 (MCP-1), and ET-1 [211]
Even more compelling, recent literature reviews have found no evidence to support the use of vitamin B12 for hair loss of any type (9)
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