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However, a long list of factors among them poor sleep, chronic stress and ultra-processed foods act to suppress your natural GLP-1 production and function, making it harder for your body to regulate weight on its own

I advise my patients to start it when whatever is happening is no longer working for them

Regarding post-operative resumption , there is no single universal timeframe, as the decision depends on multiple factors

Individuals with elevated fasting insulin (suggesting insulin resistance) may see slower initial weight loss because GLP-1 receptor signaling must first improve insulin sensitivity before maximal appetite suppression