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The combined formulation maintains a consistent ratio between the two compounds throughout the dosing interval
In exploring the characteristics of the DEGs in different types of cells in the PD brain, we found that HAMP appeared among the five genes with the greatest reduced expression in oligodendrocytes
Most patients tolerate peptide therapy very well
Because it stimulates powerful growth pathways in the brain, researchers have flagged several risks and the absence of human trials means its long-term effects are unknown
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![Structures of (a) GLP-1, (b) GIP and (c) tirzepatide [19, 88, 90]](https://www.researchgate.net/publication/370926483/figure/fig4/AS:11431281185432337@1693619320519/Structures-of-a-GLP-1-b-GIP-and-c-tirzepatide-19-88-90-Amino-acids-are.png)
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