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Instead, the medication can contribute indirectly through mechanisms such as hypoglycemia (low blood sugar level), dehydration, or electrolyte imbalance from gastrointestinal side effects, and interactions with other medications

The ones that do appear are smaller

While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population

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