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This includes reduced excitability of afferent vagal neurons (reduced vagal activation), reduced sensitivity of their receptors [33], and impairment of the vagovagal reflexes [34]

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This means that GLP-1 stimulates insulin release only when blood glucose levels are elevated, which significantly reduces (though does not eliminate) the risk of hypoglycaemia

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Glutamine metabolic pathways Glutamine is transported into cells through plasma membrane glutamine transporters such as SLC1A5, SLC38A1, and SLC38A2 17 and can then be used for the biosynthesis of hexosamine, nucleotides, and asparagine in the cytoplasm (Fig

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