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131 The direct impact of GLP-1 on these cells slows the secretion of glucagon, essential for maintaining glucose stability, especially postprandially
Refsum disease is a rare autosomal recessive disorder in which patients harbor a defect in the peroxisomal -oxidizing enzyme, phytanoyl-CoA hydroxylase (PhyH)
However, when a cell is under severe stresssuch as during a viral infection or a severe inflammatory flarethe ratio drops precipitously
Cells dosed with a serial dilution of BSO showed no cytotoxicity compared to the vehicle control, indicating that the compound did not kill the cells (Figure 5, Panel A)
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