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Studying changes in the less affected tissue (BA9) and the primarily affected brain region (CAU) provided insights into the diseases progression

OS has independently been implicated in the pathogenesis of various disorders of the brain, such as anxiety disorders, depression, bipolar disorder and schizophrenia (155157)

doi: 10.3390/nu16203522

Namely, the extracellular milieu was highly acidified in GSH mutants, and these extracellular changes blocked melanin production (which occurs at the cell wall)