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Sodium-glucose cotransporter-2 inhibitors and the risk of gout: a Danish population based cohort study and symmetry analysis

Activation of trypsin induces the leakage of lysosomes and the release of cathepsin B into the cytoplasm, which activates the cell death pathway and finally causes pancreatic injury mainly in the forms of cellular apoptosis and necrosis 21

Examples are cysteine supplements in the form of whey or N -acetylcysteine, antioxidant vitamins (B,C,E), alpha-lipoic acid, selenium or phytonutrients (i.e., Brassica vegetables and green tea) ( On the other hand, the obvious strategy to increase GSH levels is its direct administration