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A 12-week facial cream study enrolled 71 women with mild to advanced photoaging and documented increased skin density and thickness, reduced laxity, improved clarity, and reduced fine line depth

Any reference to biological activity or potential effects is based solely on preclinical or invitro findings and should not be interpreted as validated clinical outcomes

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Through a series of structure-activity relationship (SAR) studies, the authors optimized the peptide sequence and introduced a C20 fatty diacid via a -glutamic acid linker to the N-terminus