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Additionally, we sought to demonstrate specificity of RSL3 for targeting BRAF/RAS addicted cancer cells by selecting TPC-1, a PTC cell line, that lacks RAS or BRAF mutations

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However, in the posterior cortex, CAT activity was reduced in the VPA+LipRSV group compared to the VPA group, indicating that LipRSV treatment may have negatively modulated the enzymes expression or activity, either by attenuating oxidative stress and thus reducing enzymatic defense needs, or through a possible pro-oxidant effect dependent on the region and experimental conditions