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Injectable versions of these medications must be refrigerated, but some reports indicate shipments have arrived warm or without adequate cooling, potentially compromising effectiveness
Excessive alcohol use activates cytochrome P450 2E1 (CYP2E1), producing harmful reactive oxygen species (ROS) and reducing glutathione, a vital antioxidant
Many patients observe changes occurring in a few weeks
doi:10.1002/ajmg.10121
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