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Lactobacillus and Bifidobacterium are commonly used species derived from the intestinal microbiota of healthy individuals

doi: 10.1055/s-2007-1003745 173 ThondamSKDaousiCWildingJPHolstJJAmeenGIYangCet al

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The comparison between germ-free and conventionally raised mice through whole-genome bisulfite sequencing revealed that the presence of commensal microbiota in the intestinal epithelium influences TET2/3-dependent DNA methylation changes at the regulatory elements of specific genes, which helps in the maintenance of gut balance