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Description

For inflammatory bowel disease, mesalamine, corticosteroids, immunomodulators (azathioprine, methotrexate), and biologics (infliximab, adalimumab, vedolizumab, ustekinumab) all have Level 1 evidence from Phase III trials with thousands of patients

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However, in humans the data is contradictory

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Acidifiers attenuate diquat-induced oxidative stress and inflammatory responses by regulating NF-B/MAPK/COX-2 pathways in IPEC-J2 cells

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In healthy cells, p53 activation can initiate DNA repair or apoptosis depending on damage severity

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