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These create a feedback loop, all influenced by NAD+ levels
The Z-curves can fall into one of four categories: surpassing both the conventional and TSA thresholds (true positive, indicating the effectiveness of combination therapy), surpassing only the conventional threshold (false positive), falling below both the TSA and conventional thresholds without reaching the required sample size (false negative), and falling below both the TSA and conventional thresholds but having reached the required sample size (true negative, favoring the comparator arm)
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