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Conclusions This work shows that the glutathione-dependent detoxifying function of the blood-CSF barrier can be pharmacologically enhanced through the Nrf2 signaling pathway to better protect the neural fluid environment from drug and toxic accumulation during the neonatal period
While BPC-157 has a strong safety record in animal studies, there are currently no long-duration, placebo-controlled human trials available to confirm its effects over months or years
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10.1007/s11738-011-0783-z 92 LiJ.BraderG.KariolaT.PalvaE
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