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10.1016/j.biocel.2014.05.016 Int J Biochem Cell Biol

Continue daily during loading (7 to 21 days depending on skin type), then switch to 0.5 mg once or twice weekly for maintenance

It says the choice between dual and single-receptor therapy is not binary, and that a provider may recommend an adjustment to the current regimen, a temporary pause, or a structured transition rather than an immediate switch