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With adulthood and ageing, there is a reduced amount of new myelin formed in the context of a learning task or following demyelination 88,89 , in association with impaired oligodendrogenesis
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While Glucagon-Like Peptide 1 modulators (or GLP1-RMs) such as those with agonistic mechanisms of action have emerged as effective agents for weight management, MBS remains the most effective intervention for Class II (BMI 3539.9.9) and Class III (BMI 40+) obesity [6]
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