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In October 2024, the FDA declared that tirzepatide was no longer in shortage, and shortly after in February 2025 announced the same for semaglutide

This may be more prominent with semaglutide as it is known to decrease weight more rapidly than bupropion-naltrexone, thus inducing greater physiological stress on the body and thus potentially greater hair loss. They indicated that those taking Wegovy or Ozempic for weight loss may want to consider the hair loss risks, while noting that often the health benefits from the lost weight will outweigh the risks of hair shedding

For women of reproductive age, the relationship between GLP-1 receptor agonists and reproductive hormones is an area of active research

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