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Direct injection of GLP-1, exendin-4, or liraglutide to the PVH indeed suppressed food intake [71,80]
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Participants taking the highest dose (12mg) lost just over 24% of their body weight in 48 weeks, and 26% of participants lost at least 30% of their initial weight
In line with these data, here we provide, to the best of our knowledge, the first description of autophagy in melanocytes and fibroblasts from non-lesional vitiligo skin and we show that this process is part of a broader metabolic program and may act as a compensatory/protective response towards the intrinsic metabolic vulnerability
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