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The review noted that longer and larger trials are needed to confirm long-term safety, a limitation that applies to most hormone optimization approaches
Lower Risk of Gastrointestinal Side Effects The most cited drawback of standard GLP1 dosing is GI distressnausea, bloating, constipation
MT1 is listed on the WADA 2026 Prohibited List under Section S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics), prohibited both in- and out-of-competition
B-12 injections are generally very safe, with minimal side effects such as mild soreness at the injection site
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