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A few unchanged weigh-ins are not necessarily a true plateau: water retention, constipation, sodium, menstrual-cycle changes, travel, and inconsistent weighing can temporarily hide fat loss
The kidneys benefit through mechanisms that are largely body-weight-independent, while some cardiovascular benefit in leaner patients may be attenuated
Based on this evidence, tirzepatida stands out not only as a treatment, but as a new strategy for an integrated approach to metabolic control (DUARTE et al., 2020)
Therefore, pharmacotherapy plays a vital role in assisting some patients with weight loss, and its integration into treatment strategies is crucial for effective management
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