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While most L-cells expressed Snap25 , approximately 45% of Snap25 -expressing cells were positive for GLP-1, suggesting its production by other epithelial cells (Fig
Pharmaceutics, 11(11), 599
Many of these same trials also found favorable impact on kidney health
Another phase 2 RCT studying semglutide 2.4 mg vs placebo in patients with compensated NASH cirrhosis did not show any statistically significant difference in NASH resolution or improvement in liver fibrosis between the groups
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