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Chief among them: no controlled human safety data exist for the co-formulated blend, ghrelin-receptor desensitization over time is poorly characterized, sustained IGF-I elevation is a theoretical concern that has not been evaluated for this product, and GH secretagogues can affect glucose and insulin sensitivity
DOI: 10.1097/JU.0000000000003999
Individuals with certain medical conditions or who take certain medications should consult with a healthcare provider prior to initiating
This is particularly concerning given that people with obesity-related comorbidities may reap the greatest benefit from treatment. Thomsen noted the irony that patients most likely to benefit from sustained treatment were often those most likely to abandon it due to side effects or other health complications
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