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In a Phase 2 randomised controlled trial published in the New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023), adults with obesity (without type 2 diabetes) who received the highest dose of retatrutide (12 mg weekly) achieved a mean body weight reduction of approximately 24% over 48 weeks
Research: The STEP trials assessed weight loss in people with obesity receiving a once-weekly injection of semaglutide (Wegovy) over 17 months (68 weeks)
A balanced meal afterward aids muscle repair and recovery
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