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Nevertheless, the directional outcome was clear: tirzepatide demonstrated numerically higher weight loss at every analysis point, and the non-inferiority margin was not met

Very large islets were seen throughout the pancreas after 5 days of exendin-4 injection (see below)

The primary advantages of GLP-1RAs lie in glucose reduction, cardiorenal benefits, and amelioration of metabolic syndrome, all of which are substantiated by a plethora of evidence-based studies [1,2,3,4]

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