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Arachidonic acid (AA) and adrenic acid (AdA) are the main substrates of lipid peroxidation in ferroptosis [19], and the lipid peroxidation process involves three enzymes, namely, acyl-CoA synthetase long-chain family member 4 (ACSL4), lysophosphatidylcholine acyltransferase 3 (LPCAT3), and ALOX
Clinical trials indicate significant reductions in major adverse cardiovascular events, including heart attacks and strokes
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