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Phase 3 trial results released in December 2025 showed participants lost an average of 28.7% of their body weight (about 71 pounds) over 68 weeks, the highest weight loss reported for any obesity medication to date

Alternative sleep peptides or conventional approaches may work better for these individuals

"Side effects include: A smile on your face and a pep in your step." A source exclusively told Life & Style on September 5 that the Michigan-born singer had dropped more than 60 pounds since her weight loss journey began