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Some patients report fatigue during tirzepatide treatment, particularly during the early treatment phase or with dose escalation, though this is not among the most common adverse events in clinical trials
Although ACG normally codes for threonine, in the PRPS1L1 mRNA this alternative start codon directs the initiator methionine for the encoded protein
The clinical benefits of finerenone on cardiovascular and kidney events are also unlikely affected by combination therapy with GLP-1RA or SGLT2i, however, clinical evidence on additive effects of finerenone in combination with GLP-1RA or SGLT2i are still limited [56, 57]
Image: iStock/CR For more information: Maya Brownstein [email protected] ### Harvard T.H
