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The regulation of lipoxygenases by GPX4 led to a dose-dependent inhibition of the total product formation (5-HETE, LTB 4 , 12-HETE, and 15-HETE) in the presence of GPX4 activator compound 102 ( Supplementary Figure S3B )

10.12659/msm.942733 32 DuL.FanX.YangY.WuS.LiuY

Severe nausea, vomiting, or reduced oral intake may lead to dehydration or electrolyte imbalances that manifest as confusion or difficulty concentrating