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It binds to the body's own DNA and RNA released from damaged skin cells, forming complexes that activate plasmacytoid dendritic cells
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Two estimands (treatment regimen estimand and efficacy estimand), based on the ICH E9(R1) guidance 32 , were used to assess treatment efficacy from different perspectives and accounted for intercurrent events differently
Gatenby, P., Bhattacharjee, S., Wall, C., Caygill, C
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