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Phase 2: Cagrilintide introduction (weeks 9-16) Once retatrutide at 2 mg is well-tolerated, introduce cagrilintide at the lowest dose

Another breakthrough in investigating the cell death machinery of erythrocytes occurred when expression of necroptosis-associated RIPK1, RIPK3, and MLKL was confirmed in mature erythrocytes, and they were shown to undergo regulated necrosis [25, 27, 81, 82]