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Because it is a small-molecule drug, it can be taken once daily at any time of day, with or without food
J Clin Oncol 24(3):419430 Meijer AJ, Li KH, Brooks B, Clemens E, Ross CJ, Rassekh SR, Hoetink AE, van Grotel M, van den Heuvel-Eibrink MM, Carleton BC (2022) The cumulative incidence of cisplatin-induced hearing loss in young children is higher and develops at an early stage during therapy compared with older children based on 2052 audiological assessments
The highest concentrations of ascorbate in the body are found in brain and adrenal gland
Finally, while genetically predicted higher levels of the medium-chain ACs C8 and C10 were associated with increased depression risk in previous Mendelian randomization analyses, no significant association with depression presence or severity was found for levels of these ACs in the present study
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