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Concomitant inhibition of mdm2-p53 interaction and aurora kinases activates p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis and reduced endoreduplication in aml
PubMed Qiu L, Gao C, Wang H, et al
For tumour xenograft models, 1 10 6 HCC-1806 cells or 5 10 6 PC3 cells were injected into the right fourth mammary fat pad or hind flank of athymic nude NU/J mice (The Jackson Laboratory, 002019) in 100 l sterile PBS or a 1:1 mixture of cell suspension in PBS and Matrigel (Corning, 356237) using a 29-gauge 1 ml insulin syringe
Nasri, H., & Rafieian-Kopaei, M
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