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22 Eli Lilly and the Tirzepatide Portfolio: Manufacturing as a Moat While Novo Nordisk has focused heavily on the longevity of a single molecule, Eli Lillys strategy for tirzepatide (Mounjaro and Zepbound) is defined by clinical differentiation and an aggressive manufacturing moat

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They also found that ROSE-010 was most effective in patients with constipation-dominant IBS (IBS-C) and mixed IBS, with significantly less pain relief observed in patients with diarrhea-dominant or unspecified IBS [62]

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