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Diabetes Updates 5: DOI: 10.15761/DU.1000128 Figure 1

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The Leu198 (T) allele is associated with reduced GPX1 catalytic efficiency in published biochemical and epidemiological studies, with Leu/Leu homozygotes showing approximately 3040% lower GPX1 activity than Pro/Pro homozygotes in some tissue and cell line systems

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With population-based data scarce, the researchers set out to help provide more evidence

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