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Patients with a prior history of serious gastrointestinal adverse events and other known risk factors that are associated with peptic ulcer disease ( alcoholism, smoking) are at increased risk
Severe deficiencies, especially those with neurological symptoms (numbness, tingling, memory issues), often require a more intensive initial treatment plan to rapidly restore healthy B12 levels and prevent lasting nerve damage
Additionally, while AOD-9604 demonstrated excellent safety in the studied populations, individual medical histories may reveal contraindications or concerns requiring careful evaluation
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