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Access for the drug as of February 1st was 90% for patients type 2 diabetes across commercial and Medicare Part D lives, consisting of 92% commercial and 82% Part D

Significant prior efforts across the pharmaceutical industry have generally failed to identify potent and efficacious smallmolecule agonists of the GLP-1R, although a recent report has revealed the identification of a potent, nonpeptidic orally active agonist series (exemplified by LY3502970), which is structurally distinct from danuglipron

While dietary weight loss strategies typically cause some loss of lean muscle, GLP-1 and GIP/GLP-1 receptor agonists are associated with significant loss of lean mass ranging from 1545% of total weight loss,260 varying by agent