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Its not a trendits a transformation
The authors highlight biological plausibility, acknowledge limitations of retrospective administrative data, and call for randomized prospective trials to confirm causality and optimize treatment strategies
(2022) Community guidelines for GPCR ligand bias: IUPHAR review 32, Br
J Neuropathol Exp Neurol 49 : 591599 Robertson RP, Harmon J, Tran PO, Poitout V 2004 Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
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