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It works "pretty well in most people" for improving blood sugar, she said, but "for weight, there does seem to be a little bit more variation" in how well it helps people trim down
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Although it was proposed that PYY 3-36 might exert its anorexigenic effects by activating Y2 receptors on POMC neurons in the ARC, the PYY 3-36 -induced inhibition of food intake has been shown to still occur in POMC knockout mice
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