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Differentiation 1981, 19, (1), 120, Bottiglieri, T
Nanoparticle Res
In the nucleus, it combines (forms a heterodimer) with one of small Maf proteins (MAFF, MAFG, MAFK) and binds to the antioxidant response element (ARE) in the upstream promoter region of many antioxidative genes, and initiates their transcription
In patients whose inflammation is also linked to metabolic issues, we often pair BPC-157 with interventions discussed in our clinical write-up on GHK-Cu and weight loss, which explains how copper peptide signaling integrates with body recomposition goals
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