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Historically, endocrinologists and internists dominated the GLP-1 prescription scene, but their share dropped from 93% in 2020 to 83% in 2025

Short-term pharmacotherapy has not been shown to produce longer-term health benefits and cannot be generally recommended

If symptoms are particularly troublesome, your doctor may recommend: Slower dose escalation than standard protocols Temporary dose reduction Switching to a different GLP-1 agonist, as individual responses vary Short-term use of anti-diarrhoeal medications such as loperamide for acute episodes, though this should only be done under medical supervision and avoided if you have blood in your stool, fever, or suspected infection If you're also taking insulin or sulfonylureas, monitor your blood glucose more frequently during periods of reduced appetite or diarrhoea, as you may need dose adjustments to prevent hypoglycaemia

Always check the syringe label