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According to a recent meta-analysis, the percentage of people suffering chronic fatigue 12 weeks or more after exposure to COVID-19 was 0.32, whereas cognitive impairment was 0.22 [66]

Other sources of superoxide can be enzymatic reactions that transfer electrons to the ETC such as mitochondrial glycerol 3-phosphate dehydrogenase (mGPDH), and the last step of -oxidation, electron-trasferring flavoprotein ubiquinone oxidoreductase (ETFQOR) or dehydrogenases such as pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxoacid dehydrogenase (BCKDH)

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Synthetic GLP-1 and GIP agonists bind to their respective receptors and elicit the same response as the endogenous hormones would