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New England Journal of Medicine (2022) 4
The pivotal trials enrolled hundreds of subjects and used CT-measured visceral adipose tissue (VAT) as the primary endpoint, a harder measure than BMI or waist circumference
Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(736) amide infused at near-physiological insulinotropic hormone and glucose concentrations
Sulfonylureas have been used for over 50 years and include medications such as gliclazide, glimepiride, and glipizide
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