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BMJ Open 10 (8), e033687
Additionally, GPxs due to their subcellular compartmentalization (cytoplasmic, membrane, ER, and mitochondrial localizations) control the local concentration gradient of peroxides and thereby regulate the activation/deactivation of redox-responsive signaling pathways [1, 8,9,10]
BRCA is a systemic and complex disease, and what we briefly discuss here may involve many pathogenic factors
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