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Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease

Journal of Clinical Pharmacology, 63(12), 1121-1130

Some facts attested that a reduction in the number of mAchRs and nAchRs in basal forebrain cholinergic neurons, and a 40%-50% decrease in cerebral acetylcholine level are considered pathogenic elements for dementia and AD (41, 42)