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This extra-high insulin level could trigger a sharp crash in blood sugar levels, leading to symptoms such as fatigue, irritability, difficulty concentrating, dizziness, anxiety, nausea, and shakiness

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GLP-1RAs improve hyperglycemia by enhancing insulin secretion through increases in -cell cytoplasmic cyclic adenosine monophosphate [53], which activates protein kinase A (PKA) and, thus, increases in intracellular calcium and triggers insulin exocytosis in a glucose-dependent manner [54]